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endocarditis, natieve klep - empirisch

Advices

≥ 18 years

Indications: Subacuut begin en langdurig beloop (indolente presentatie)

Priority Medication Remarks
Medication:

amoxicilline + clavulaanzuur iv 1000/200mg 6dd

+

gentamicine iv 3mg/kg 1dd 5 days

Medication:

ceftriaxon iv 2000mg 2dd

+

gentamicine iv 3mg/kg 1dd 5 days

Remarks:

Bij niet IgE-gemedieerde penicillineallergie.

Medication:

vancomycine iv 1000mg 2dd

+

gentamicine iv 3mg/kg 1dd 5 days

Remarks:

Bij IgE-gemedieerde penicillineallergie.

≥ 18 years

Indications: Acuut en fulminant beloop of intraveneus drugsgebruik

Priority Medication Remarks
Medication:

flucloxacilline iv 2000mg 6dd

+

vancomycine iv 1000mg 2dd

Medication:

cefuroxim iv 1500mg 3dd

+

vancomycine iv 1000mg 2dd

Remarks:

Bij niet IgE-gemedieerde penicillineallergie.

Medication:

vancomycine iv 1000mg 2dd

+

gentamicine iv 3mg/kg 1dd 5 days

Remarks:

Bij IgE-gemedieerde penicillineallergie.

General comments

Voor spiegelcontrole bij Vancomycine en Gentamicine: zie tabblad ''overig''

Sources

  1. Pubmed.gov publication # 19713420

    Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009 Oct;30(19):2369-413.

  2. Pubmed.gov publication # 22086858

    Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrob Chemother. 2012 Feb;67(2):269-89.

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-409525.2
Updated: 10/26/2018 - 21:02
Status: Published