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meningitis - Cryptokok (cryptococ)

Advices

≥ 18 years
Priority Medication Remarks
Medication:

amfotericine B conventioneel (Fungizone) iv 1mg/kg 1dd 14 days

+

flucytosine iv 25mg/kg 4dd 14 days

Remarks:

Amfo b (Fungizone): 0.7-1 mg/kg 1dd

Indien flucytosine niet beschikbaar; liposomaal amfotericine B + fluconazol 800mg 1dd1 2 weken

Medication:

fluconazol po loading dose 800mg, 400mg 1dd 8 weeks

Remarks:

bij stabiele en goed responderende patiënt na 2 weken

Medication:

fluconazol po 200mg 1dd

Remarks:

secundaire profylaxe bij persisterende afweerstoornis. HIV: totdat CD4 gedurende ≥3 maanden >200 cellen/mm3

General comments

N.B.: Start met 1mg testdosis Amfotericine B (Fungizone) in 20-30 minuten ivm ernstige infusiereacties.

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-434267.2
Updated: 09/30/2025 - 15:26
Status: Published