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endocarditis, kunstklep - vergroenende streptokokken

Advices

≥ 18 years

Indications: Kunstklep - MIC penicilline kleiner dan 0.1 mg/l

Priority Medication Remarks
Medication:

benzylpenicilline iv 2million. IU 6dd 6 weeks

Medication:

ceftriaxon iv 2000mg 1dd 6 weeks

Remarks:

Bij niet IgE-gemedieerde penicillineallergie.

Medication:

vancomycine iv 1000mg 2dd 6 weeks

+

gentamicine iv 3mg/kg 1dd 2 weeks

Remarks:

Bij IgE-gemedieerde penicillineallergie. Let op: voorkeur voor penicilline desensibilisatie (op de IC) iom allergoloog en consulent infectieziekten.

≥ 18 years

Indications: Kunstklep - MIC penicilline 0.1 mg/l - 0.5 mg/l

Priority Medication Remarks
Medication:

benzylpenicilline iv 3million. IU 6dd 6 weeks

+

gentamicine iv 3mg/kg 1dd 2 weeks

Medication:

ceftriaxon iv 2000mg 2dd 6 weeks

+

gentamicine iv 3mg/kg 1dd 2 weeks

Remarks:

Bij niet IgE-gemedieerde penicillineallergie.

Medication:

vancomycine iv 1000mg 2dd 6 weeks

+

gentamicine iv 3mg/kg 1dd 2 weeks

Remarks:

Bij IgE-gemedieerde penicillineallergie. Let op: voorkeur voor penicilline desensibilisatie (op de IC) iom allergoloog en consulent infectieziekten.

≥ 18 years

Indications: Kunstklep - MIC penicilline groter dan 0.5 mg/l

Priority Medication Remarks
Medication:

amoxicilline iv 2000mg 6dd 6 weeks

+

gentamicine iv 3mg/kg 1dd 6 weeks

Medication:

vancomycine iv 1000mg 2dd 6 weeks

+

gentamicine iv 3mg/kg 1dd 6 weeks

Remarks:

Bij penicillineallergie of penicilline hoog resistent (MIC penicilline groter dan 2.0 mg/l).

General comments

Voor spiegelcontrole bij Vancomycine en Gentamicine: zie tabblad ''overig''

Sources

  1. Endocarditis.pdf

    UMCG protocol Endocarditis

  2. Pubmed.gov publication # 19713420

    Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009 Oct;30(19):2369-413.

  3. Pubmed.gov publication # 22086858

    Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrob Chemother. 2012 Feb;67(2):269-89.

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-409371.2
Updated: 10/26/2018 - 21:00
Status: Published